Endocrine Abstracts

Background: Vitamin B12 is crucial for placental development and fetal growth. B12 deficiency is associated with maternal obesity and adverse pregnancy outcomes. B12 is essential for the synthesis of S-Adenosyl methionine (SAM) which serves as a methyl donor in various cellular processes including DNA and RNA methylation. Pregnant women with low B12 have higher triglycerides, lower HDL and lower DNA methylation of cholesterol transcription factor. However, the...